引用文本：周侦, 李引. 《2024年韩国胃癌转化治疗专家共识》解读与思考[J/CD]. 消化肿瘤杂志（电子版）, 2025, 17(3):308-315.

作者：周侦，李引

单位：中山大学附属第一医院胃肠外科中心，广东 广州 510080

Authors：Zhou Zhen, Li Yin

Unit：Gastrointestinal Surgery Center, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong, China

摘要：

胃癌的转化治疗是针对初始不可切除或临界可切除的胃癌患者，经过全身系统治疗后实施以R0切除为目的的手术策略。目前Ⅳ期胃癌标准疗法仍以姑息性化学治疗为主，转化手术虽有潜在获益但缺乏高水平循证证据。为此，韩国胃癌协会组织17位外科、内科肿瘤等领域的专家，采用德尔菲法就预先制定的与胃癌转化治疗相关的主题进行了匿名投票，最终形成9条推荐意见。该共识为我国开展胃癌的转化治疗提供了重要参考，但在临床应用的过程中，仍需结合国内外其他专家的意见以及我国患者特点加以优化。本文围绕共识中关于转化治疗的定义、最佳时机、淋巴结清扫范围、手术方式等关键内容进行解读，以期为胃癌转化治疗的临床实践提供借鉴与启示。

关键词：胃癌；转移；转化治疗；诊疗指南；解读

Abstract：

Conversion therapy for gastric cancer refers to a treatment strategy in which patients with initially unresectable or marginally resectable disease receive systemic therapy first, followed by surgery with the aim of achieving an R0 resection. At present, palliative chemotherapy remains the standard of care for stage Ⅳ gastric cancer. Although conversion surgery offers potential benefits, there is a paucity of high-level evidence to support its routine use. In response, the Korean Gastric Cancer Association convened 17 experts in surgical and medical oncology and employed a Delphi process to vote anonymously on a pre-specified set of topics related to conversion therapy in gastric cancer, ultimately formulating 9 consensus recommendations. While this consensus provides an important reference for the implementation of conversion therapy in China, it must be refined in light of additional international expert opinions and the specific characteristics of Chinese patients. This article interprets the key elements of the consensus regarding the definition of conversion therapy, optimal timing, extent of lymphadenectomy, and choice of surgical procedure, aiming to offer insights and guidance for the application of conversion therapy in gastric cancer.

Key words：Gastric cancer; Metastasis; Conversion therapy; Clinical practice guidelines; Interpretation

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