引用文本：程思, 李文星. 纳米材料在结直肠癌治疗中的研究进展[J/CD]. 消化肿瘤杂志（电子版）, 2025, 17(1):72-77.

作者：程思，李文星

单位：山西医科大学第二医院 普通外科，山西 太原 030000

Authors：Cheng Si, Li Wenxing

Unit：General Surgery Department, the Second Affiliated Hospital of Shanxi Medical University, Taiyuan 030000, Shanxi, China

摘要：

纳米材料作为一种新兴的材料，因其独特的物理、化学和生物学特性在结直肠癌的治疗中发挥重要的作用。近年来，纳米技术飞速发展，在结直肠癌的放疗、化疗等辅助治疗中的应用越来越广泛。光热疗法、光动力疗法是目前新型的肿瘤治疗方法，纳米材料在提高其治疗效果方面也显示出明显优势。本文综述了近年来纳米材料在结直肠癌的放疗、化疗、免疫治疗、光热疗法、光动力疗法、基因治疗及联合治疗中的研究进展，以期为纳米材料在结直肠癌治疗中的应用和推广提供参考依据。

关键词：结直肠癌；纳米材料；光热疗法；光动力疗法

Abstract：

As a new material, nanomaterials play an important role in the treatment of colorectal cancer due to their unique physical, chemical and biological properties. In recent years, with the rapid development of nanotechnology, its application in the adjuvant therapy such as radiotherapy and chemotherapy for colorectal cancer becomes more and more extensive. Photothermal therapy and photodynamic therapy are new tumor treatment methods at present, and nanomaterials also show obvious advantages in improving the therapeutic effect. In this paper, the research progress of nanomaterials in radiotherapy, chemotherapy, immunotherapy, photothermal therapy, photodynamic therapy, gene therapy and combination therapy for colorectal cancer in recent years was reviewed, in order to provide reference for the application and promotion of nanomaterials in colorectal cancer treatment.

Key words：Colorectal cancer; Nanomaterials; Photothermal therapy; Photodynamic therapy

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