Traditional Chinese medicine combined with targeted drugs in treatment of middle and advanced gastric cancer
单位：川北医学院附属医院 药剂科，四川 南充 637000
Authors: Zeng Yan, You Ran, Han Bin
Unit: Department of Pharmacy, Affiliated Hospital of North Sichuan Medical University, Nanchong 637000, Sichuan, China
Gastric cancer is one of the most common gastrointestinal malignant tumors, which seriously affects the health of patients. China is a high-incidence country for gastric cancer, with morbidity and mortality two times higher than the world average. The mortality of advanced gastric cancer is high, with a 5-year survival rate of about 10%, and the average survival period is 6 months. Chemotherapy is an important means for the treatment of advanced gastric cancer, but it has some limitations in improving the long-term survival of patients due to the toxicity and side effects. Targeted drugs provide more means for the treatment of gastric cancer. The commonly used targeted drugs for gastric cancer include trastuzumab, ramucirumab and apatinib. Traditional Chinese medicine has accumulated rich experience in the treatment of gastric cancer, which could prolong the survival period of patients, improve the quality of life and reduce side effects. It provides supplementary means for the clinical comprehensive treatment of gastric cancer. The existing research are summarized in traditional Chinese medicine combined with targeted drugs in gastric cancer. It provides new ideas for developing clinical anti-tumor treatment of traditional Chinese medicine.
Key Words: Traditional Chinese medicine；Targeted therapy；Gastric cancer；Side effects