作者：唐小波1，吴祖光2

单位：1. 惠州市第三人民医院 胃肠外科 广州医科大学附属惠州医院 胃肠外科，广东 惠州 516000； 2.梅州市人民医院 胃肠外科，广东 梅州 514000

Authors:  TANG Xiaobo1, WU Zuguang2

Unit:   1.Department of Gastrointestinal, The Third People's Hospital of Huizhou, Huizhou Hospital Affiliated to Guangzhou Medical University, Huizhou 516000, Guangdong, China； 2.Department of Gastrointestinal, Meizhou People's Hospital, Meizhou 514000, Guangdong, China

摘要：

回顾性分析在梅州市人民医院诊断的肺腺癌空肠转移致肠梗阻病例资料并复习相关文献。患者空肠肿物大小约6X5X3 cm, 肿瘤浸润肠壁全层并突破浆膜层, 免疫组化结果显示:CK7(+), TTF-1 (+), NapsinA (散在+), Vimentin (+), CK20 (-), CDX-2 (-), Villin (-), CD56 (-), CgA (-), Syn (-), Ki67 (约60%+), 肠系膜淋巴结见肿瘤转移(3枚/3枚), 结合临床信息, 确诊肺腺癌空肠转移, 患者于术后4个月死亡。肺癌小肠转移的实际发生率远远高于临床确诊率, 鉴别小肠原发性肿瘤或继发性肿瘤难度高, 肺癌空肠转移的治疗效果较差。

关键词： 肺腺癌; 空肠转移瘤; 肠梗阻

Abstract：

Retrospective analysis of the cases of jejunal obstruction caused by metastasis of lung adenocarcinoma diagnosed in our hospital and review of relevant literature. The size of the jejunal mass was about 6X5X3 cm. The tumor infiltrated the whole intestinal wall and broke through the serosa layer. Immunohistochemical results shows:CK7(+), TTF-1(+), NapsinA(+), Vimentin(+), CK20(-), CDX-2(-), Villin(-), CD56(-), CgA(-), Syn(-), Ki67(60%+). Mesenteric lymph nodes showed metastasis of tumors (3/3). Combined with clinical information, metastasis of lung adenocarcinoma to jejunum was confirmed. The patient died 4 months after operation. The actual incidence of small intestinal metastasis of lung cancer is far higher than that of clinical diagnosis; it is difficult to differentiate primary or secondary tumors of small intestine; the clinical therapeutic effect of small intestinal metastasis of lung cancer is poor.

Key Words:  Lung adenocarcinoma; Jejunal metastasis; Intestinal obstruction